Make sure that you are in back office of your online store. Click on Advance Parameters > Performance
1. Clear Cache Button
Click on Clear cache icon to clear your cache.
2. Force Compilation
If you want to clear everytime while you edit module’s setting, css and tpl files. You may need to do force compilation and set no for cache and save it.
1. disable combine, compress and cache
2. disable media severs
3. No caching
4. Third Party Cache Modules
If you have installed any third party module related with accelerate, cache you may need to disable it.
Note: Once you are ok with changing tpl,css and js file you can again enable performance setting